참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Tin atom | HCID 5352426 | — |
| 반응물 | 7-(Chlorosulphonyl)-2,3-dihydro-1,4-benzodioxin-5-carboxylic acid | HCID 6455316 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 7-Mercapto-1,4-benzodioxane-5-carboxylic acid | HCID 20544694 | 90% |
반응 단계
243 g of 7-chlorosulfonyl-1,4-benzodioxane-5-carboxylic acid and 654 cm3 of acetic acid were introduced into a balloon flask provided with an agitator and a condenser. The mixture was heated to 90° C. and then cooled to 45° C. 389 g of tin and 1,744 cm3 of hydrochloric acid were then added. The mixture was heated to 55°-60° C., cooled and poured into water. The precipitate was dried off, washed and dried. 166 g of 7-mercapto-1,4-benzodioxane-5-carboxylic acid were obtained (M.P.: 191°-192° C.; yield: 90%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04255580 |
|---|
| 출처 데이터셋 | uspto-grants-1981_03 |
|---|
| ORD ID | ord-5458f89a342a4d6bbee077740f32d53e |
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| 출처 메모 | uspto-grants-1981_03 |
|---|
