HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 7-Ethylsulfonyl-1,4-benzodioxane-5-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 7-Ethylsulfonyl-1,4-benzodioxane-5-carboxylic acid | HCID 20544758 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Product | 7-Ethylsulfonyl-1,4-benzodioxane-5-carbonyl chloride | HCID 20544728 | 100% |
Reaction Steps
243 g of thionyl chloride, a few drops of dimethyl formamide and 139 g of 7-ethylsulfonyl-1,4-benzodioxane-5-carboxylic acid were introduced into a balloon flask provided with a condenser. The mixture was heated and then the thionyl chloride in excess was distilled off under vacuum. 148 g of 7-ethylsulfonyl-1,4-benzodioxane-5-carbonyl chloride were obtained (M.P.: 146°-147° C.; yield: 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04255580 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-5ad8f432a3ea43a79e993b8f5e28d15d |
| Source note | uspto-grants-1981_03 |