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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1274021Generated: October 28, 2026

Indomethacin → HCID 178498032, compound

https://huagongshe.com/reaction/1274021

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
ReactantMethyl 4-chloroanthranilateHCID 80001—
Reagent1-MethylimidazoleHCID 1390—
Reagent6-Cyano-N,N,2-trimethyl-7-oxo-4,8-dioxa-2,5-diazadec-5-en-3-iminium hexafluorophosphateHCID 57348955—
SolventAcetonitrileHCID 6342—
ProductHCID 178498032HCID 1784980322.75%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-13893c0d188a448c939ee31879cfd445
Source noteAniline amide coupling reaction