HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Propenoic acid, 3-phenyl- → 3-Phenylprop-2-enoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Propenoic acid, 3-phenyl- | HCID 8784 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Aluminum | HCID 5359268 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 3-Phenylprop-2-enoyl chloride | HCID 66023 | 90% |
Reaction Steps
1 mmol of the cinnamic acid (4) was solved in anhydrous benzene and stirred in an aluminum foil covered flask. 3 mmol thionyl chloride was added and refluxed under stirring overnight. The solvent was removed under vacuum and the product (5) recrystallized from hexane. The derivatives of cinnamoyl chloride were obtained in a 90% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06156232 |
| Source dataset | uspto-grants-2000_12 |
| ORD ID | ord-d6d6da01f7d04df99a3fe94f1af306d3 |
| Source note | uspto-grants-2000_12 |