Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-Nitrophenyl 3-O-methyl-beta-L-fucopyranoside → p-Aminophenyl 3-o-methyl-beta-l-fucoside
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-Nitrophenyl 3-O-methyl-beta-L-fucopyranoside | HCID 18336706 | — |
| 반응물 | Dichloromethane methanol | HCID 21226129 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Adams' catalyst | HCID 345198 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | p-Aminophenyl 3-o-methyl-beta-l-fucoside | HCID 18336697 | — |
반응 단계
3.81 g (12.73 nmmol) of p-nitrophenyl 3-O-methyl-β-L-fucopyranoside are dissolved in methanol and, after addition of platinum dioxide, hydrogenated in a hydrogen atmosphere at a slight overpressure. After filtering off the catalyst and precipitating with ether, 3 g (88%) of the target product are obtained. [TLC: dichloromethane/methanol 9:1 Rf =0.53].
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06156754 |
| 출처 데이터셋 | uspto-grants-2000_12 |
| ORD ID | ord-35d82c4d43694122806f15de9bff94ef |
| 출처 메모 | uspto-grants-2000_12 |