HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 7-Chloro-1,4-benzodioxane-5-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 7-Chloro-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid | HCID 18613662 | — |
| Product | 7-Chloro-1,4-benzodioxane-5-carbonyl chloride | HCID 20544703 | 100% |
Reaction Steps
32.2 g of 7-chloro-1,4-benzodioxane-5-carboxylic acid and 64 ml of thionyl chloride were introduced into a balloon flask provided with an agitator, a thermometer and a condenser. The mixture was heated under reflux and then the thionyl chloride in excess was distilled off under vacuum. 35 g of 7-chloro-1,4-benzodioxane-5-carbonyl chloride were obtained (M.P.: 140° C.; yield: 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04255580 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-7e6383343fde4001b220fb0d5d87cba8 |
| Source note | uspto-grants-1981_03 |