2-[(Acetylthio)methyl]-3-phenylpropionic Acid → HCID 22120801, compound

HRID 1274225Notes

Reaction equation

HRID 1274225 reaction equation
[C:1]([S:4][CH2:5][CH:6]([CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:7]([OH:9])=O)(=[O:3])[CH3:2].[CH2:17]([C:24]1[O:28][C:27]([C:29](=[N:35]O)[C:30]([O:32][CH2:33][CH3:34])=[O:31])=[CH:26][CH:25]=1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>C(Cl)(Cl)Cl>[CH2:33]([O:32][C:30](=[O:31])[CH:29]([C:27]1[O:28][C:24]([CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:25][CH:26]=1)[NH:35][C:7](=[O:9])[CH:6]([CH2:5][S:4][C:1](=[O:3])[CH3:2])[CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[CH3:34]

Participants

4

Reactant 2

HCID 99917962-[(Acetylthio)methyl]-3-phenylpropionic AcidHCID 86756081HCID 86756081, compound

Product 1

HCID 22120801HCID 22120801, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The title compound was prepared from 2-(acetylthiomethyl)-3-phenylpropionic acid (US 4329495) and ethyl (5-benzyl)furan-2-yl-2-hydroxyiminoacetate (Description 42) by the procedure of Description 40. νmax (CHCl3) 3428, 1741 and 1683cm-1. m/z 479 M+). [Found (HRMS): m/z 479.1768. Calc. for C27H29NO5S; 479.1766].

Sources & evidence

ORD record
ord-346c3c559ddd43aeb5e4b13b902a10fb
Source dataset
uspto-grants-2000_12
Patent number
US06156774

Reaction notes

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