Water → HCID 53849665, compound

Participants

Reaction Steps

To a solution of 4-[4-(benzyloxy)-phenoxy]-3-nitrobenzaldehyde (2.48 g, 7.1 mmol) in ethanol (100 ml) was added sodium borohydride (0.27 g, 7.3 mmol), followed by stirring at room temperature for 2 hours. The reaction solution was poured into water and extracted with ethyl acetate. The solvent was dried and evaporated under reduced pressure. The residue was purified by silica gel column chromatography [eluent; chloroform - ethyl acetate (4:1)] to give 4-[4-(benzyloxy)phenoxy]-3-nitrobenzyl alcohol (2.48 g).

Provenance & Evidence