Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 7-Nitro-1,4-benzodioxane-5-carbonyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 7-Nitro-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid | HCID 12464533 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 7-Nitro-1,4-benzodioxane-5-carbonyl chloride | HCID 20544745 | 100% |
반응 단계
112 ml of thionyl chloride, 56 g of 7-nitro-1,4-benzodioxane-5-carboxylic acid were introduced into a 250 ml balloon flask provided with a stirrer, a thermometer and a reflux condenser. The mixture was stirred and 1 ml of dimethylformamide was added with heating. After stirring for one hour at the reflux temperature, the excess of thionyl chloride was removed by distillation under vacuum. 61 g of 7-nitro-1,4-benzodioxane-5-carbonyl chloride were obtained (M.P.: 108° C.; yield: 100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04255580 |
| 출처 데이터셋 | uspto-grants-1981_03 |
| ORD ID | ord-13d36516524b43fa94487556b6178ebb |
| 출처 메모 | uspto-grants-1981_03 |