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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1275011Generated: October 26, 2026

5-Bromonaphthalene-1-carboxylic acid → 5-Bromo-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]naphth-1-yl Carboxamide

https://huagongshe.com/reaction/1275011

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromonaphthalene-1-carboxylic acidHCID 697605—
Reactant4-Methoxy-3-(4-methylpiperazin-1-yl)anilineHCID 10331101—
Product5-Bromo-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]naphth-1-yl CarboxamideHCID 22118896—

Reaction Steps

The title compound was prepared from 5-bromo-1-naphthoic acid (J. Chem. Soc., 1950, 991) and 4-methoxy-3-(4-methylpiperazin-1-yl)aniline (EP0533268A1) using a similar procedure to Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06159979
Source datasetuspto-grants-2000_12
ORD IDord-67f3c750e9df4b7b970699adb11e204b
Source noteuspto-grants-2000_12