1-Naphthyl Isothiocyanate → HCID 22118882, compound

HRID 1275018Notes

Reaction equation

HRID 1275018 reaction equation
[C:1]1([N:11]=[C:12]=[S:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[CH3:14][O:15][C:16]1[CH:22]=[CH:21][C:19]([NH2:20])=[CH:18][C:17]=1[N:23]1[CH2:28][CH2:27][N:26]([CH3:29])[CH2:25][CH2:24]1>>[CH3:14][O:15][C:16]1[CH:22]=[CH:21][C:19]([NH:20][C:12]([NH:11][C:1]2[C:10]3[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=3)[CH:4]=[CH:3][CH:2]=2)=[S:13])=[CH:18][C:17]=1[N:23]1[CH2:24][CH2:25][N:26]([CH3:29])[CH2:27][CH2:28]1

Participants

3

Reactant 2

HCID 110801-Naphthyl IsothiocyanateHCID 103311014-Methoxy-3-(4-methylpiperazin-1-yl)aniline

Product 1

HCID 22118882HCID 22118882, compound

Procedure

The title compound was prepared from 1-naphthyl isothiocyanate and 4-methoxy-3-(4-methylpiperazin-1-yl)aniline (EP0533268A1) using a similar procedure to Example 6.

Sources & evidence

ORD record
ord-39779c63c47c40b9876b1d8d9ef47cb5
Source dataset
uspto-grants-2000_12
Patent number
US06159979

Reaction notes

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