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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1275128Generated: November 2, 2026

Methyl 2-(2-hydroxyethyl)-4,5,6,7-tetrahydronaphtho[2,1-b]furan-7-carboxylate → 2-(2-(3-Phenyl-7-propylbenz[4,5]isoxazol-6-yloxy)ethyl)-4,5,6,7-tetrahydronaphtho[2,1-b]furan-7-carboxylic acid

https://huagongshe.com/reaction/1275128

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(2-hydroxyethyl)-4,5,6,7-tetrahydronaphtho[2,1-b]furan-7-carboxylateHCID 18672470—
Reactant3-phenyl-7-propyl-1,2-Benzisoxazol-6-olHCID 135800811—
Product2-(2-(3-Phenyl-7-propylbenz[4,5]isoxazol-6-yloxy)ethyl)-4,5,6,7-tetrahydronaphtho[2,1-b]furan-7-carboxylic acidHCID 69625154—

Reaction Steps

Using the procedure from Example 1, steps F and G, the title compound was prepared from methyl 2-(2-hydroxyethyl)-4,5,6,7-tetrahydronaphtho[2,1-b]furan-7-carboxylate and 3-phenyl-7-propyl-6-hydroxybenz[4,5]isoxazole as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06160000
Source datasetuspto-grants-2000_12
ORD IDord-3f6a8d6cfbbd4a8d86f5c3aea41df844
Source noteuspto-grants-2000_12