N-Hydroxyphthalimide → HCID 53700881, compound

Participants

Reaction Steps

Dibromoacetic acid (0.1 mmole) and N-hydroxyphthalimide (0.1 mmole) are mixed and coupled in THF in the presence of DCC for 2 hours. The product, (N-dibromoacetoxyphthalimide) is isolated by filtration and dried. Radical-induced dehalogenation (0.1 mmole scale) using the general method with tributyltin deuteride furnished the N-deuterioacetoxyphthalimide with two atoms of deuterium. The N-ditritioacetoxyphthalimide can be prepared the same way.

Provenance & Evidence