Hydrochloric Acid → HCID 22118419, compound

Participants

Reaction Steps

16.0 Grams (54 mmol) of 6-carboxy-4,4-ethylenedioxy-5-methylthiochroman-1,1-dioxide was dissolved in 90 ml of acetone and 30 ml of water, and 10 ml of a 12N hydrochloric acid aqueous solution was added. The mixture was stirred at room temperature for 2 days. After the completion of the reaction, the reaction mixture was concentrated, and extracted with ethyl acetate. An organic layer was washed with a saturated sodium chloride aqueous solution and dried over anhydrous sodium sulfate, and the solvent was distilled off under reduced pressure to give 13.7 g (yield: quantitative) of the titled compound.

Provenance & Evidence