HCID 10675002, compound → HCID 9827468, compound

Participants

Reaction Steps

2 g of 1-[(2-dimethylaminoethyl)aminocarbonyl]-5,6-dimethyl-9-(5-benzyloxycarbonylpentan-oyloxy)-6H-pyrido[4,3-b]carbazole dissolved in 600 ml of methanol are hydrogenated in the presence of 0.2 g of palladium-on-barium sulphate for 36 hours under 3.5×105Pa of hydrogen at room temperature. The catalyst is removed by filtration and the filtrate is concentrated to dryness. The residue is taken up in ethanol and concentrated almost to dryness, and diethyl ether is added. The precipitate is suction-filtered and dried at 40° C. under 133 Pa. 1.9 g of the desired product are obtained, m.p.(cap): 88-90° C.

Provenance & Evidence