HCID 10299911, compound → HCID 22887904, compound

HRID 1275598Notes

Reaction equation

HRID 1275598 reaction equation
N1C=CC=CC=1N1CCN(C[C:14]2[N:18]=[C:17]([NH:19][C@H:20]([C:25]([N:27]3[CH2:34][CH2:33][CH2:32][C@H:28]3[C:29]([OH:31])=[O:30])=[O:26])[CH2:21][CH:22]([CH3:24])C)[S:16][N:15]=2)CC1.[CH3:35][O:36]C1N=C(NC(CC[C@H](C)[C@@H](C([N-]CCC(C)C)=O)N)=O)SN=1.[CH3:59]OC1N=C(NC(CC(C)C[C@@H](C([N-]CCC(C)C)=O)N)=O)SN=1>>[CH3:35][O:36][C:14]1[N:18]=[C:17]([NH:19][C@H:20]([C:25]([N:27]2[CH2:34][CH2:33][CH2:32][C@H:28]2[C:29]([OH:31])=[O:30])=[O:26])[C@H:21]([CH2:22][CH3:24])[CH3:59])[S:16][N:15]=1

Participants

3

Reactant 2

HCID 10299911HCID 10299911, compoundHCID 178494321HCID 178494321, compound

Product 1

HCID 22887904HCID 22887904, compound

Procedure

which has the following chemical formula: ##STR19## {3-[4-(2-pyridyl)piperazinylmethyl]-1,2,4-thiadiazol-5-yl}-leucyl-proline, which has the following chemical formula: ##STR20## 5-{3-methoxy-1,2,4-thiadiazolyl}carbamoyl-leucyl isoamylamide 5-{3-methoxy-1,2,4-thiadiazolyl}carbamoyl-isoleucyl isoamylamide

Sources & evidence

ORD record
ord-7960b66140fd47fa98651da7e88a37df
Source dataset
uspto-grants-2000_12
Patent number
US06162791

Reaction notes

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