Methyl 4-bromobenzoate → HCID 22117427, compound

HRID 1275618Notes

Reaction equation

HRID 1275618 reaction equation
[CH:1]([C:4]1[C:5]([OH:18])=[CH:6][C:7]2[C:8]([CH3:17])([CH3:16])[CH2:9][CH2:10][C:11]([CH3:15])([CH3:14])[C:12]=2[CH:13]=1)([CH3:3])[CH3:2].Br[C:20]1[CH:29]=[CH:28][C:23]([C:24]([O:26][CH3:27])=[O:25])=[CH:22][CH:21]=1>>[CH:1]([C:4]1[C:5]([O:18][C:20]2[CH:29]=[CH:28][C:23]([C:24]([O:26][CH3:27])=[O:25])=[CH:22][CH:21]=2)=[CH:6][C:7]2[C:8]([CH3:16])([CH3:17])[CH2:9][CH2:10][C:11]([CH3:15])([CH3:14])[C:12]=2[CH:13]=1)([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 12081Methyl 4-bromobenzoateHCID 22117428HCID 22117428, compound

Product 1

HCID 22117427HCID 22117427, compound

Procedure

In a manner similar to Example 1(a) above, by the reaction of 2 g (8.1 mmol) of 3-isopropyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthol with 1.45 g (6.7 mmol) of methyl 4-bromo-benzoate, 840 mg (33%) of the expected methyl ester of melting point 115-6° C. were obtained.

Workup

  1. customwere obtained

Sources & evidence

ORD record
ord-eaed241f62db41d18b3a794a15ebd00f
Source dataset
uspto-grants-2000_12
Patent number
US06162815

Reaction notes

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