HCID 11164107, compound → HCID 54401965, compound

HRID 1275768Notes

Reaction equation

HRID 1275768 reaction equation
[F:1][C:2]([F:24])([F:23])[C:3]1[CH:4]=[C:5]([C:9]2([OH:22])[C:21]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[C:15]3[C:10]2=[CH:11][CH:12]=[CH:13][CH:14]=3)[CH:6]=[CH:7][CH:8]=1.C[O:26][C:27](=[O:50])[C@H:28]([C@@H:47]([CH3:49])O)[NH:29]C(OCC1C2C=CC=CC=2C2C1=CC=CC=2)=O>>[F:1][C:2]([F:23])([F:24])[C:3]1[CH:4]=[C:5]([C:9]2([O:22][C@H:47]([CH3:49])[C@@H:28]([C:27]([OH:50])=[O:26])[NH2:29])[C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][C:15]=3[C:16]3[C:21]2=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH:6]=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 11164107HCID 11164107, compoundHCID 22117473HCID 22117473, compound

Product 1

HCID 54401965HCID 54401965, compound

Procedure

from 9-(3-trifluoromethylphenyl)-9H-fluoren-9-ol (Example 3m) and Nα -(9-fluorenylmethoxycarbonyl)-L-threonine methyl ester;

Sources & evidence

ORD record
ord-7ed0dea3d7624273b21c40248607b69c
Source dataset
uspto-grants-2000_12
Patent number
US06162824

Reaction notes

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