HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-5,5-dimethyl-2-cyclohexen-1-one → 3,4,6,7,9,10-hexahydro-3,3,6,6-tetramethyl-9-[3-(2-pyrazinyloxy)phenyl]-1,8-(2H,5H)-acridinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-5,5-dimethyl-2-cyclohexen-1-one | HCID 136680 | — |
| Reactant | 3-(2-Pyrazinyloxy)-benzaldehyde dimethyl acetal | HCID 22117816 | — |
| Product | 3,4,6,7,9,10-hexahydro-3,3,6,6-tetramethyl-9-[3-(2-pyrazinyloxy)phenyl]-1,8-(2H,5H)-acridinedione | HCID 22117855 | — |
Reaction Steps
Reaction of 3-amino-5,5-dimethyl-2-cyclohexen-1-one with 3-(2-pyrazinyloxy)-benzaldehyde dimethyl acetal in an analogous manner to that described in Example 1 gave 3,4,6,7,9,10-hexahydro-3,3,6,6-tetramethyl-9-[3-(2-pyrazinyloxy)phenyl]-1,8-(2H,5H)-acridinedione. Crystallization from dimethylformamide/water gave a pale brown crystalline solid of melting point 204-207° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06162918 |
| Source dataset | uspto-grants-2000_12 |
| ORD ID | ord-f8bbf951ab2d425d8d43e041ba2fd738 |
| Source note | uspto-grants-2000_12 |