HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dimethyl L-aspartate → N-[2-[1,1-Dimethylethoxycarbonylamino]thiazol-4-yl]acetyl-L-aspartic acid, dimethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dimethyl L-aspartate | HCID 111207 | — |
| Reactant | 2-(2-((tert-Butoxycarbonyl)amino)thiazol-4-yl)acetic acid | HCID 15480006 | — |
| Product | N-[2-[1,1-Dimethylethoxycarbonylamino]thiazol-4-yl]acetyl-L-aspartic acid, dimethyl ester | HCID 86756129 | — |
Reaction Steps
The subtitle compound was prepared from 2-[1,1-dimethylethoxycarbonylamino]thiazol-4-ylacetic acid (Chem. Pharm. Bull. 1993, 41, 758) (1.0 g) and L-aspartic acid dimethyl ester (1.15 g) according to the method of example 10 step (i). Yield 1.36 g. Used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06162808 |
| Source dataset | uspto-grants-2000_12 |
| ORD ID | ord-42bf9ceed13f4a34bb0ec946f8ea67d9 |
| Source note | uspto-grants-2000_12 |