HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl iminodiacetate → N-[2-Aminothiazol-4-yl]-N-[ethoxycarbonylmethyl]glycine, ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl iminodiacetate | HCID 80502 | — |
| Reactant | 2-(2-((tert-Butoxycarbonyl)amino)thiazol-4-yl)acetic acid | HCID 15480006 | — |
| Product | N-[2-Aminothiazol-4-yl]-N-[ethoxycarbonylmethyl]glycine, ethyl ester | HCID 131722230 | — |
Reaction Steps
The subtitle compound was prepared from 2-[[1,1-dimethylethoxy]carbonylamino]4-thiazoleacetic acid (0.75 g) (Chem. Pharm. Bull. 1993, 41, 758) and diethyl iminodiacetate (0.83 g) according to the method of example 15 step (i) followed by step (ii). Yield 0.91 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06162808 |
| Source dataset | uspto-grants-2000_12 |
| ORD ID | ord-71c514e2420247f79a635bff5762e473 |
| Source note | uspto-grants-2000_12 |