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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 127607Generated: October 28, 2026

Z-Val-ONp → Z-Val-Thr-Leu-OtBu

https://huagongshe.com/reaction/127607

Reaction equation

Participants

RoleNameHCIDCharge
ReactantZ-Val-ONpHCID 112124—
ReactantH-Thr-Leu-OtBuHCID 131712120—
SolventDimethylformamideHCID 6228—
ProductZ-Val-Thr-Leu-OtBuHCID 13171211972%

Reaction Steps

Coupling of 7.85 g Z-Val-ONp with 5.53 p H-Thr-Leu-OtBu in 160 ml DMF in the way described in C(2) provides Z-Val-Thr-Leu-OtBu in 72% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04256736
Source datasetuspto-grants-1981_03
ORD IDord-e083a7e508bb45058ca4efdea4973573
Source noteuspto-grants-1981_03