反应详情

A mixture of 8-(4-methylpiperazin-1-yl)naphthalene-2-carboxylic acid benzyl ester (0.20 g, 5.55 mmol) and Pd(OH) on carbon (0.11 g) in 2 mL of ethanol was hydrogenated on a Parr shaker apparatus at 50 psi for 5 hr. After diluting with ethanol and filtering through diatomaceous earth, the solvent was removed in vacuo to yield the title product as a foam, 138 mg.

1. filtrationfiltering through diatomaceous earth
2. customthe solvent was removed in vacuo