HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 2-Bromo-3,4-dihydro-7-methoxy-1(2H)-naphthalenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-one | HCID 81276 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 2-Bromo-3,4-dihydro-7-methoxy-1(2H)-naphthalenone | HCID 311906 | 87.2% |
Reaction Steps
To a 10° C. solution of 25 g (0.142 mol) of 7-methoxy-3,4-dihydro-1 (2H)-naphthalenone in 1 liter ether was added dropwise (maintaining reaction temperature at about 10° C.) 37.9 g (0.237 mol) of bromine. The reaction solution was concentrated on a rotating evaporator and the residue crystallized from ether to give 31.6 g (87%) of present title compound, m.p. 79-80° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06166031 |
| Source dataset | uspto-grants-2000_12 |
| ORD ID | ord-3d39bcc79ac24b209e0115e05d760577 |
| Source note | uspto-grants-2000_12 |