2-(2-Chloroethoxy)tetrahydro-2H-pyran → HCID 19075003, compound

HRID 1276322Notes

Reaction equation

HRID 1276322 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2([CH3:13])[CH3:12].Cl[CH2:15][CH2:16][O:17]C1CCCCO1>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([CH2:15][CH2:16][OH:17])[C:6](=[O:11])[C:5]2([CH3:13])[CH3:12]

Participants

3

Procedure

Prepared from 5-chloro-3,3,dimethyl-1,3-dihydro-2H-indol-2-one (prepared by the method of Endler and Becker; Organic Syntheses Coll. vol.4, page 657) and 2-(2-chloroethoxy)tetrahydro-2H-pyran as described above.

Workup

  1. customprepared by the method of Endler and Becker

Sources & evidence

ORD record
ord-bc8d3b44a5a4442a9985fbb6552d157f
Source dataset
uspto-grants-2000_12
Patent number
US06166040

Reaction notes

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