2-(2-Chloroethoxy)tetrahydro-2H-pyran → HCID 22116115, compound

HRID 1276324Notes

Reaction equation

HRID 1276324 reaction equation
[CH3:1][C:2]1([CH3:14])[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([O:11][CH3:12])[CH:9]=2)[NH:4][C:3]1=[O:13].Cl[CH2:16][CH2:17][O:18]C1CCCCO1>>[CH3:1][C:2]1([CH3:14])[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([O:11][CH3:12])[CH:9]=2)[N:4]([CH2:16][CH2:17][OH:18])[C:3]1=[O:13]

Participants

3

Reactant 2

HCID 2549512-(2-Chloroethoxy)tetrahydro-2H-pyranHCID 104651545-Methoxy-3,3-dimethyl-1,3-dihydro-2H-indol-2-one

Product 1

HCID 22116115HCID 22116115, compound

Procedure

Prepared from 3,3-dimethyl-5-methoxy-1,3-dihydro-2H-indol-2-one (prepared by the method of Endler and Becker; Organic Syntheses Coll. vol. 4 page 657) and 2-(2-chloroethoxy)tetrahydro-2H-pyran as described above.

Workup

  1. customprepared by the method of Endler and Becker

Sources & evidence

ORD record
ord-76a9d7a46ca444b3a689daa6fa3f665c
Source dataset
uspto-grants-2000_12
Patent number
US06166040

Reaction notes

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