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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1276373Generated: November 1, 2026

(3-phenyl-1H-pyrazol-1-yl)acetic acid → N-[1-(benzyl)-pyrrolidin-3-(RS)-ylmethyl]-2-(3-phenylpyrazol-1-yl)acetamide

https://huagongshe.com/reaction/1276373

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-phenyl-1H-pyrazol-1-yl)acetic acidHCID 2737161—
Reactant(1-Benzylpyrrolidin-3-yl)methanamineHCID 3157467—
Reactant3-Aminomethyl-1-(3,4-dichlorobenzyl)pyrrolidineHCID 22115310—
ProductN-[1-(benzyl)-pyrrolidin-3-(RS)-ylmethyl]-2-(3-phenylpyrazol-1-yl)acetamideHCID 22115333—

Reaction Steps

Proceeding as described above but substituting 4-(2,5-dimethylphenyl)-4-oxobutyric acid with 2-(3-phenylpyrazol-1-yl)acetic acid and 3-aminomethyl-1-(3,4-dichlorobenzyl)pyrrolidine with 3-aminomethyl-1-benzylpyrrolidine gave N-[1-(benzyl)-pyrrolidin-3-(RS)-ylmethyl]-2-(3-phenylpyrazol-1-yl)acetamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06166015
Source datasetuspto-grants-2000_12
ORD IDord-9331105c7cde47a18da9d367f99c3fec
Source noteuspto-grants-2000_12