Diisopropylethylamine → HCID 70273689, compound

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Reaction Steps

The title compound was prepared from 20 mg of 1-Benzyl-3-(SR)-formyl-4-(SR)-phenylpyrrolidine, 28 mg of 2, 3, 4, 5-tetrahydro-1H-benzo[d]-azepine-picrate salt, 0.013 mL of DIEA and 24 mg of sodium triacetoxyborohydride using a procedure analogous to that described in Example 9, Step B to provide 14.5 mg of the title compound. RF : 0.53 (50% EtOAc in hexanes). 1H NMR (300 MHz, CDCl3): δ2.42-3.02 (m, 16H), 3.67 (ABq, J=13 Hz, 2H), 7.00-7.38 (m, 14H). Mass Spectrum (ESI): 397.1 (M+H).

Provenance & Evidence