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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1276568Generated: November 1, 2026

Ethanol → Ethyl difluoro(iodo)acetate

https://huagongshe.com/reaction/1276568

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantPotassium FluorideHCID 522689—
Reactant1,1,2,2-Tetrafluoro-2-iodoethyl sulfurofluoridateHCID 12596365—
ProductEthyl difluoro(iodo)acetateHCID 273720074%

Reaction Steps

Ethyl iododifluoroacetate (73.4 g, 74% yield) could also be prepared from 2-iodo-1,1,2,2-tetrafluoroethyl fluorosulfate (130.4 g, 0.4 mol), potassium fluoride (23.2 g, 0.4 mol) and ethanol (150 mL) according to the procedure described in Experiment (3a).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06166157
Source datasetuspto-grants-2000_12
ORD IDord-ac45c7189159486da81ca204f8df001a
Source noteuspto-grants-2000_12