1-Propanol → HCID 22116527, compound

Participants

Reaction Steps

To 10 g (0.099 g) of propyl isothiocyanate was added 50 mL of n-propanol. The reaction mixture was heated to reflux for 3 h and cooled to room temperature. An aliquot was removed and concentrated under reduced pressure to give the title compound, 1H NMR (300 MHz, CDCl3): δ0.94-1.02 (m,6H); 1.49-1.83 (m,4H); 3.22 (q), 3.51 (q,2H total); 4.37 (t), 4.45 (t,2H total), 6.25 (br s), 6.78 (br s,1H total). The remaining reaction mixture was concentrated under reduced pressure as above to provide 13.5 g of oil which was used without further purification.

Provenance & Evidence