HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetyl chloride → (10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-[2-(2,3-dihydro-spiro[indene-1,4'-piperidin]-1'-yl)-ethyl]-amine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Reactant | Iem 2115 | HCID 81481 | — |
| Reactant | 2,3-Dihydrospiro(indene-1,4'-piperidine) | HCID 15637616 | — |
| Product | (10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-[2-(2,3-dihydro-spiro[indene-1,4'-piperidin]-1'-yl)-ethyl]-amine hydrochloride | HCID 22116580 | — |
Reaction Steps
The title compound, m.p. 170° C. and MS: m/e=423.4 (M+H+), was prepared in accordance with the general method of example 1 from 5-amino-10,11-dihydro-5H-dibenzo[a,d]cycloheptene, chloroacetyl chloride, 2,3-dihydro-spiro[1H-indene-1,4'-piperidine] and Hcl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06166209 |
| Source dataset | uspto-grants-2000_12 |
| ORD ID | ord-ef94ddade38945019dfe8c211cf5589b |
| Source note | uspto-grants-2000_12 |