Hydrogen Peroxide → 1-(2-Hydroxy-2-methylpropoxy)-2,2,6,6-tetramethylpiperidin-4-one

Participants

Reaction Conditions

Reaction Steps

A solution of 1.0 g (15 mmol) of 50% aqueous hydrogen peroxide in 5 mL of tert-butyl alcohol is added over 30 minutes at 60° C. to a mixture of 0.5 g (2.9 mmol) of 1-oxyl-2,2,6,6-tetramethylpiperidin-4-one, 0.1 g (0.16 mmol) of N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminomanganese(II) chloride (Jacobsen's catalyst), and 10 mL of tert-butyl alcohol. The reaction is stirred overnight at 60° C. Gas chromatography shows 2.5% of the title compound is present in the reaction mixture.

Provenance & Evidence