3-Butyn-1-OL → HCID 20643060, compound

HRID 1276689Notes

Reaction equation

HRID 1276689 reaction equation
I[C:2]1[N:3]([CH2:18][C:19]2[C:28]3[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH:22]=[CH:21][CH:20]=2)[CH:4]=[C:5]2[C:10]=1[C:9](=[O:11])[N:8]([CH3:12])[C:7](=[O:13])[N:6]2[CH2:14][CH:15]([CH3:17])[CH3:16].[CH2:29]([OH:33])[CH2:30][C:31]#[CH:32]>>[OH:33][CH2:29][CH2:30][C:31]#[C:32][C:2]1[N:3]([CH2:18][C:19]2[C:28]3[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH:22]=[CH:21][CH:20]=2)[CH:4]=[C:5]2[C:10]=1[C:9](=[O:11])[N:8]([CH3:12])[C:7](=[O:13])[N:6]2[CH2:14][CH:15]([CH3:17])[CH3:16]

Participants

3

Reactant 2

HCID 135663-Butyn-1-OLHCID 18362930HCID 18362930, compound

Product 1

HCID 20643060HCID 20643060, compound

Procedure

The title compound was prepared from 5-iodo-3-methyl-1(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione and 3butyn-1-ol in a manner analogous to the method of Example 13 above.

Sources & evidence

ORD record
ord-5dc7d7855e8941b48e27be288ebbc113
Source dataset
uspto-grants-2000_12
Patent number
US06166206

Reaction notes

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