HCID 20285755, compound → HCID 20285764, compound

HRID 127673Notes

Reaction equation

HRID 127673 reaction equation
CC1C=CC2NN=NC=2C=1.[O:11]1[CH2:16][CH2:15][N:14](NC(Cl)=O)[CH2:13][CH2:12]1.C(N(C1C=CC=CC=1)[C:24]([N:26]1[C:30]2[CH:31]=[CH:32][C:33]([CH3:35])=[CH:34][C:29]=2[N:28]=[N:27]1)=[O:25])C>>[O:11]1[CH2:12][CH2:13][N:14]([C:24]([N:26]2[C:30]3[CH:31]=[CH:32][C:33]([CH3:35])=[CH:34][C:29]=3[N:28]=[N:27]2)=[O:25])[CH2:15][CH2:16]1

Participants

4

Reactant 3

HCID 20285755HCID 20285755, compoundHCID 22047996HCID 22047996, compoundHCID 178423511HCID 178423511, compound

Product 1

HCID 20285764HCID 20285764, compound

Procedure

Compound 2 was prepared by treating 5-methylbenzotriazole (C) (8.89 g, 67 m.mole) with morpholinocarbamoyl chloride (E) (10 g, 67 m.mole) in a manner similar to that described in the preparation of (1). The product which included the 6-methyl isomer, was crystallized from methanol (100 ml). Yield, 13.2 g, 81 percent, m.p. 81° to 82° C. (uncorr.).

Workup

  1. customwas crystallized from methanol (100 ml)
  2. customYield

Sources & evidence

ORD record
ord-061783e0b8f343c6a39c8d96672ca045
Source dataset
uspto-grants-1981_03
Patent number
US04256881

Reaction notes

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