HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Iodobenzoic acid → 2-Iodobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Iodobenzoic acid | HCID 6941 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Iodobenzoyl chloride | HCID 69112 | — |
Reaction Steps
2-Iodobenzoic acid (65.92 g, 0.266 mol), oxalyl chloride (40.5 g, 0.319 mol) , CH2Cl2 (200 mL) and DMF (10 drops) were stirred at RT overnight. The reaction solution was concentrated, toluene was added and the solution concentrated to afford the crude 2-iodobenzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06166057 |
| Source dataset | uspto-grants-2000_12 |
| ORD ID | ord-a3c3627ccc2f407bb82c796b8b236038 |
| Source note | uspto-grants-2000_12 |