2,2-Bis(diphenylphosphinomethyl)-3-cyclopenta-dienyl-1-propanol → 3-Cyclopentadienyl-2-(5-dibenzophospholylmethyl)-2-(diphenylphosphinomethyl)-1-propanol

Participants

Reaction Steps

The preparation was carried out using a method similar to that for 3a. 1.6 g (4.8 mmol) of 2a were deprotonated with 2 ml (4.8 mmol) of n-BuLi solution and reacted with 1.2 equivalents of lithium dibenzophospholide solution to give the crude product 3c. The colorless oil which remained was dissolved in methylene chloride and absorbed on kieselguhr. This was followed by flash chromatography on silica gel (23*4 cm; eluant: PE/diethyl ether in a ratio of 8.5:1.5, RF =0.27). This gave 1.36 g (55%) of 3c in the form of a colorless, viscous oil.

Provenance & Evidence