Formic Acid → 6-Benzenesulfonylcarbamoyl-1-(biphenyl-4-ylmethyl)benzimidazole

Participants

Reaction Conditions

Reaction Steps

A mixture of 0.400 g of N-benzenesulfonyl-4-amino-3-(biphenyl-4-ylmethylamino)benzamide and 2 ml of formic acid was stirred at 90° C. for 3 hours. The reaction solution was concentrated, and was precipitated with methanol. The crystals precipitated were separated through filtration, and were dried to give 0.243 g of 6-benzenesulfonylcarbamoyl-1-(biphenyl-4-ylmethyl)benzimidazole (241).

Provenance & Evidence