HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dioxane-2,6-dione → Mcn 4308
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dioxane-2,6-dione | HCID 78232 | — |
| Reactant | 4-Benzhydrylpiperidine | HCID 88278 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Mcn 4308 | HCID 196442 | — |
Reaction Steps
In a similar operation, 5.0 grams (20 millimoles) of 4-benzhydrylpiperidine in 140 milliliters of dichloromethane was reacted with 2.3 grams (20 millimoles) of diglycolic anhydride in 200 milliliters of dichloromethan to obtain the desired [2-(4-benzhydrylpiperidino)-2-oxoethoxy]acetic acid product as a white solid which after purifying with ethyl acetate-hexane mixture had a m.p. of 139.5°-141° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04256891 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-0ca4a9a8b8564ad8b2d091818c6f5ca3 |
| Source note | uspto-grants-1981_03 |