3-Methoxypropylamine → HCID 5153298, compound

HRID 1277326Notes

Reaction equation

HRID 1277326 reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=1.[CH3:11][O:12][CH2:13][CH2:14][CH2:15][NH2:16]>>[N+:8]([C:5]1[CH:6]=[CH:7][C:2]([NH:16][CH2:15][CH2:14][CH2:13][O:12][CH3:11])=[CH:3][CH:4]=1)([O-:10])=[O:9]

Participants

3

Reactant 2

HCID 16723-MethoxypropylamineHCID 9590p-Fluoronitrobenzene

Product 1

HCID 5153298HCID 5153298, compound

Procedure

One heats to reflux for 5 hours 0.2 mole (28.2 g) of parafluoronitrobenzene in 102 ml of γ-methoxypropylamine. One then pours the cooled reaction mixture into 200 g of crushed ice. The intended product precipitates first in the form of an oil which crystallizes rapidly. After recrystallization in methanol and vacuum drying the product melts at 56° C. Analysis gives the following results:

Workup

  1. additionOne then pours
  2. customThe intended product precipitates first in the form of an oil which
  3. customcrystallizes rapidly
  4. customAfter recrystallization in methanol
  5. dry with materialvacuum drying the product melts at 56° C
  6. customAnalysis gives the
  7. customfollowing results

Sources & evidence

ORD record
ord-5c1d4245a4cc47f6a506ae50f43aaca4
Source dataset
uspto-grants-1981_07
Patent number
US04277244

Reaction notes

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