Methyl iodide → HCID 23453746, compound

HRID 1277360Notes

Reaction equation

HRID 1277360 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]1[C:15]2([CH2:19][CH2:18][C:17](=[S:20])[NH:16]2)[CH:13]2[CH2:14][CH:10]1[CH2:11][CH2:12]2.[CH3:21][I:22]>CC(C)=O>[IH:22].[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]1[C:15]2([CH2:19][CH2:18][C:17]([S:20][CH3:21])=[N:16]2)[CH:13]2[CH2:14][CH:10]1[CH2:11][CH2:12]2

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 23453641HCID 23453641, compound

Product 1

HCID 23453746HCID 23453746, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

56 mmoles of 3-(2-methoxyphenyl)-spiro[bicyclo[2.2.1]-heptane-2,2'-pyrrolidine]-5'-thione and 7 ml of methyl iodide in 220 ml of acetone are refluxed for 10 minutes. After cooling the mixture, the residue is filtered off. Pale yellow compound of melting point 228° C. (decomposition)

Workup

  1. temperatureAfter cooling the mixture
  2. filtrationthe residue is filtered off

Sources & evidence

ORD record
ord-2e96df13ba7b43989de52ff9eb6f5a47
Source dataset
uspto-grants-1981_07
Patent number
US04277470

Reaction notes

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