HCID 23453657, compound → HCID 23453765, compound

HRID 1277367Notes

Reaction equation

HRID 1277367 reaction equation
[N+:1]([C:4]1([CH2:18][CH2:19][C:20]([O:22]C)=O)[CH:9]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH:8]2[CH2:16][CH2:17][CH:5]1[CH:6]=[CH:7]2)([O-])=O>C(O)C.[Ni]>[C:10]1([CH:9]2[C:4]3([CH2:18][CH2:19][C:20](=[O:22])[NH:1]3)[CH:5]3[CH2:17][CH2:16][CH:8]2[CH2:7][CH2:6]3)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

4

Reactant 1

HCID 23453657HCID 23453657, compound

Product 1

HCID 23453765HCID 23453765, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 702EthanolSolvent

Procedure

55 mmoles of methyl β-(2-nitro-3-phenyl-bicyclo[2.2.2]-oct-5-en-2-yl)-propionate in 100 ml of ethanol are hydrogenated, with 3 g of Raney nickel, at 50° C.and under 70 bars. The catalyst is filtered off, the solvent is evaporated off and the residue is recrystallized from isopropanol.

Workup

  1. filtrationThe catalyst is filtered off
  2. customthe solvent is evaporated off
  3. customthe residue is recrystallized from isopropanol

Sources & evidence

ORD record
ord-e17c64e492fd43dc8410b933b6ffcf5e
Source dataset
uspto-grants-1981_07
Patent number
US04277470

Reaction notes

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