Methyl iodide → HCID 86737840, compound

HRID 1277369Notes

Reaction equation

HRID 1277369 reaction equation
[C:1]1([CH:7]2[C:14]3([CH2:18][CH2:17][C:16](=[S:19])[NH:15]3)[CH:11]3[CH2:12][CH2:13][CH:8]2[CH2:9][CH2:10]3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:20][I:21]>CC(C)=O>[IH:21].[CH3:20][S:19][C:16]1[CH2:17][CH2:18][C:14]2([CH:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)[CH:8]3[CH2:13][CH2:12][CH:11]2[CH2:10][CH2:9]3)[N:15]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 23453664HCID 23453664, compound

Product 1

HCID 86737840HCID 86737840, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

24 mmoles of 3-phenyl-spiro[bicyclo[2.2.2]-octane-2,2'-pyrrolidine]-5'-thione and 3 ml of methyl iodide are heated in 50 ml of acetone for 10 minutes. After cooling, the mixture is filtered. Crystals of melting point 192°-193° C. are obtained.

Workup

  1. temperatureAfter cooling
  2. filtrationthe mixture is filtered
  3. customCrystals of melting point 192°-193° C. are obtained

Sources & evidence

ORD record
ord-7803e0c172fe4adbbbb46793fb95a61b
Source dataset
uspto-grants-1981_07
Patent number
US04277470

Reaction notes

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