HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → HCID 12802546, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | HCID 12802575 | HCID 12802575 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 12802546 | HCID 12802546 | — |
Reaction Steps
In 50 ml of MeOH is dissolved 3.3 g of Z-(D)-Ala-Gly-Phe-OEt and after 1 mlof hydrazine hydrate is added, the solution is allowed to stand at room temperature for 2 days. It is then treated with diethyl ether, collected by filtration and recrystallized from ethanol. 3.0 g (94%); m.p. 196°-197° C; Rf1 =0.34; [α]D27 +2.4°(c=0.37, DMF).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04277394 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-48e756224a9047efb05c0095e2250fb5 |
| Source note | uspto-grants-1981_07 |