HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boc-Tyr-ONB → BOC-Tyr-(D)-Lys(Cl-Z)-Gly-Phe-NHNH-COCH3
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boc-Tyr-ONB | HCID 6995563 | — |
| Reactant | BOC-(D)-Lys(Cl-Z)-Gly-Phe-NHNH-COCH3 | HCID 131712289 | — |
| Product | BOC-Tyr-(D)-Lys(Cl-Z)-Gly-Phe-NHNH-COCH3 | HCID 131712288 | 81.7% |
Reaction Steps
Using BOC-(D)-Lys(Cl-Z)-Gly-Phe-NHNH-COCH3 (0.70 g) and BOC-Tyr-ONB (0.50 g), the desired compound (0.71 g) is obtained in a similar manner to(V) of Example 26. m.p. 196°-198° C., [α]D23 -2.0°(c=0.47, DMF), Rf1 =0.46
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04277394 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-cee5a002558f42d98bf33ae04a9320e0 |
| Source note | uspto-grants-1981_07 |