Water → HCID 23454140, compound

Participants

Reaction Steps

To a solution of 2-phthalimidoacetonitrile (11.2 g, 60 mmol) in trifluoroacetic acid (25 ml) at 0°-5° was added 2-cyclopentyl-1,1-dimethylethanol (8.52 g, 60 mmol) over 20 minutes. The reaction mixture was then stirred at 25° for 2 hours, poured into stirred water (200 ml), and the precipitated solid collected. The crude product was crystallized from ethanol-water (1:1) giving colourless needles m.p. 159°-160°. Found: C, 69.66; H, 7.18; N, 8.22. C19H24N2O3 requires C, 69.51; H, 7.32; N, 8.53.

Provenance & Evidence