1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine → 1-Methyl-4a-phenyl-2,3,4,4a,5,6,7,8-octahydroisoquinoline

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Reaction Steps

Following the above procedure but substituting 1-methyl-4-(3-methoxyphenyl)-1,2,5,6-tetrahydropyridine for 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine, there was prepared 1-methyl-4a-(3-methoxyphenyl)-2,3,4,4a,5,6,7,8-octahydroisoquinoline. The compound distilled in the range 144°-6° C. at 0.1 torr.; yield 19.3 g.

Provenance & Evidence