HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 4-(Bromomethyl)-2-fluoro-1,1′-biphenyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 2-FLUORO-4-METHYLBIPHENYL | HCID 10899366 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 4-(Bromomethyl)-2-fluoro-1,1′-biphenyl | HCID 13020229 | — |
Reaction Steps
In this instance one equivalent of Br2 was added dropwise to a refluxing solution of 2-fluoro-4-methylbiphenyl and CCl4 while being irradiated with a sunlamp. NMR analysis showed the ratio of starting material:monobromide:dibromide to be 21:67:12.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04278516 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-51da4e8bee8d4704add9170ffa9141b9 |
| Source note | uspto-grants-1981_07 |