2-Butoxybenzoyl chloride → HCID 23453044, compound

HRID 1277675Notes

Reaction equation

HRID 1277675 reaction equation
[NH2:1][CH:2]([CH3:16])[CH2:3][C:4]1[CH:9]=[CH:8][C:7]([CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:6][CH:5]=1.[CH2:17]([O:21][C:22]1[CH:30]=[CH:29][CH:28]=[CH:27][C:23]=1[C:24](Cl)=[O:25])[CH2:18][CH2:19][CH3:20]>>[CH2:17]([O:21][C:22]1[CH:30]=[CH:29][CH:28]=[CH:27][C:23]=1[C:24]([NH:1][CH:2]([CH3:16])[CH2:3][C:4]1[CH:9]=[CH:8][C:7]([CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:6][CH:5]=1)=[O:25])[CH2:18][CH2:19][CH3:20].[CH2:17]([O:21][C:22]1[CH:30]=[CH:29][CH:28]=[CH:27][C:23]=1[C:24]([NH:1][CH:2]([CH3:16])[CH2:3][C:4]1[CH:5]=[CH:6][C:7]([CH2:10][C:11]([OH:13])=[O:12])=[CH:8][CH:9]=1)=[O:25])[CH2:18][CH2:19][CH3:20]

Participants

4

Reactant 2

HCID 159219152-Butoxybenzoyl chlorideHCID 23453092HCID 23453092, compound

Product 2

HCID 23453044HCID 23453044, compoundHCID 23453096HCID 23453096, compound

Procedure

In an analogous manner, by the reaction of ethyl 4-(2-aminopropyl)-phenylacetate with o-butoxybenzoyl chloride, there is obtained, via ethyl 4-[2-(2-butoxybenzamido)-propyl]-phenylacetate (oil), 4-[2-(2-butoxybenzamido)-propyl]-phenylacetic acid; m.p. 91°-92° C., after recrystallization from isopropanol/water.

Sources & evidence

ORD record
ord-1f3b3a4fc94a47558e3f842f29634a29
Source dataset
uspto-grants-1981_07
Patent number
US04278680

Reaction notes

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