反应详情

28 g 3-(2-hydroxyethoxy)-2-ethyl-acrylic acid methyl ester was hydrogenated in 100 ml methanol in the presence of 2 g 5% palladium-carbon catalyst at atmospheric pressure. 24 g 3-(2-hydroxyethoxy)-2-ethyl-propionic acid methyl ester boiling at 104°-107° C./0.1 torr (84% yield) was recovered from the filtered hydrogenation mixture after evaporation of the solvent and vacuum distillation and identified by its carbon content of 54.35% (54.54% calculated for C8H16O4).

1. custom24 g 3-(2-hydroxyethoxy)-2-ethyl-propionic acid methyl ester boiling at 104°-107° C./0.1 torr (84% yield) was recovered from the filtered hydrogenation mixture
2. customafter evaporation of the solvent and vacuum distillation