2,2-Dimethoxyethylmethylamine → HCID 23451739, compound

HRID 1277836Notes

Reaction equation

HRID 1277836 reaction equation
[CH2:1]([C:6]1[CH:7]=[C:8]([CH:25]=[CH:26][CH:27]=1)[O:9][C:10]1[CH:15]=[CH:14][C:13]([NH:16][C:17](=O)[O-:18])=[CH:12][C:11]=1[CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[CH2:2][CH2:3][CH2:4][CH3:5].[CH3:28][O:29][CH:30]([O:34][CH3:35])[CH2:31][NH:32][CH3:33]>C1(C)C=CC=CC=1>[CH2:1]([C:6]1[CH:7]=[C:8]([CH:25]=[CH:26][CH:27]=1)[O:9][C:10]1[CH:15]=[CH:14][C:13]([NH:16][C:17]([N:32]([CH2:31][CH:30]([O:34][CH3:35])[O:29][CH3:28])[CH3:33])=[O:18])=[CH:12][C:11]=1[CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[CH2:2][CH2:3][CH2:4][CH3:5]

Participants

4

Reactant 2

HCID 85032,2-DimethoxyethylmethylamineHCID 23451788HCID 23451788, compound

Product 1

HCID 23451739HCID 23451739, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

[4-(3-Pentylphenoxy)-3-pentylphenyl]carbamate (0.1 mole) and toluene (100 ml) are charged into a glass reaction vessel fitted with a mechanical stirrer, thermometer and condenser. N-(2,2-dimethoxyethyl)methanamine (0.15 mole) is added to the vessel and the mixture is refluxed for 16 hours. Solvent is then removed by mild warming under reduced pressure to yield the desired product N-[4-(3-pentylphenoxy)-3-pentylphenyl]-N'-(2,2-dimethoxyethyl)-N'-methylurea.

Workup

  1. customfitted with a mechanical stirrer
  2. temperaturethe mixture is refluxed for 16 hours
  3. customSolvent is then removed
  4. temperatureby mild warming under reduced pressure

Sources & evidence

ORD record
ord-aa96d17517d64f0991957807266a47c0
Source dataset
uspto-grants-1981_07
Patent number
US04279637

Reaction notes

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